Available Technologies
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Some of these ideas are being developed into start-up companies that need investment or partners to further advance their research and development. Others are strong ideas in search of another party to pick up and carry further, perhaps in the form of a licence agreement.
For more start-ups, many of which are looking for investment, see Investment Portfolio.
Drugs, vaccines and drug delivery
| Therapeutic Area | Name | Description | Status | Contact |
|---|---|---|---|---|
| Oncology | c-Kit mutation selective inhibitor discovery programme |
Unique kinase ATP site-directed scaffold for the synthesis of highly potent c-Kit mutant selective inhibitors for cancer therapy.
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Available for licensing | |
| Vaccines and drug delivery | Vaccine for Staphylococcus aureus |
A staphylococcal superantigen-like based vaccine for preventing staph infections.
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Available for licensing | |
| Vaccines and drug delivery | CLipPA: Cystine Lipidation on a Peptide or Amino acid |
A proprietary platform for the site-specific conjugation of lipids to peptides.
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Available for licensing | |
| Vaccines and drug delivery | Ester Bond Scaffolding |
A new protein platform technology: A novel 鈥榮uperglue鈥� utilising ester bonds to join multiple different units together to access many innovative applications.
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Available for licensing | |
| Regenerative and tissue engineering | Cell Replacement Therapy for Huntington鈥檚 Disease |
A novel cell replacement therapy for Huntington鈥檚 Disease directly reprogramming human skin cells into brain stem cells.
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Available for licensing | |
| Regenerative and tissue engineering | Kelch鈥檚 medium |
New cell growth media for keratinocytes: A cholera-toxin free and xenogeneic feeder cell-free media which maximises keratinocyte proliferation.
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Available for licensing | |
| Regenerative and tissue engineering | Skin Engineering |
System for rapid growth of full-thickness autologous skin.
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Available for licensing | |
| Regenerative and tissue engineering | Novel transparent protein biomaterials with versatile applications |
New biomaterials comprised of crystallin proteins being developed for ocular surgery and stem cell delivery applications.
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Available for licensing | |
| Ophthalmology | Diabetic Rat Strain | These rats develop hyperglycaemia and have retinal microaneurysms and macroaneurisms at four weeks of age. | Available for licensing | |
| Oncology | Novel therapy for glioblastoma | A new drug candidate for activating tumour cell death and improving uptake of chemotherapy drugs. | Available for licensing | |
| Infectious diseases | Lipidated Polymyxins |
Novel analogue of polymyxin B as a new last-line therapy against antibiotic-resistant strains of Gram-negative bacteria.
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Available for licensing | |
| Oncology | HPK-1 Selective Inhibitor Discovery Program |
Selective HPK-1 antagonist for treating cancer. Related to the Kinase KING programme.
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Available for licensing | |
| Oncology | Kinase inhibitors for the next generation (Kinase KING) |
A platform for rapid development of highly selective next-generation protein kinase inhibitors.
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Available for licensing | |
| Oncology | Novel DNA analogues of duocarmycins as new toxins for ADCs |
Newly synthesised analogues of duocarmycin utilised as an optimised toxic payload in antibody-drug conjugates (ADCs) for cancer treatment.
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Available for licensing | |
| Oncology | Novel DNA-dependent protein kinase inhibitors |
Novel DNA-PK inhibitors and related hypoxia-activated prodrugs for sensitising tumour cells to radiotherapy by blocking a key DNA repair pathway.
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Available for licensing | |
| Oncology | FGFR inhibitors |
A targeted approach to deliver potent irreversible FGFR inhibitors utilising hypoxia selective activation for cancer therapy.
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Available for licensing | |
| Oncology | CSF鈥�1R inhibitor |
A unique scaffold and structure-based approach to synthesise highly potent CSF-1R inhibitors for cancer therapy.
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Available for licensing | |
| Oncology | TamoRx |
Developing immunotherapy to help patients鈥� immune systems destroy cancer cells.
|
Start-Up | |
| Neurological | Selective Antagonist of 5-HT2A receptor |
Novel compound exhibiting highly selective antagonism of the 5-HT2A receptor to treat psychiatric disorders.
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Available for licensing |
Medical devices, diagnostics, assays and digital health technologies
| Therapeutic Area | Name | Description | Status | Contact |
|---|---|---|---|---|
| Audiology | TrueSilence |
An evidence-based system that treats multiple aspects of tinnitus using a mobile device.
|
Start-Up | |
| Cardiology | HeartLab |
AI-powered heart scanning and reporting software.
|
Start-Up | |
| Cardiology | Atrial fibrillation: Real-time and robust mapping of heart activation |
Novel catheter-agnostic software platform to identify ablation targets for atrial fibrillation (AF) using signal processing and 3D voltage mapping to create fast substrate maps.
Download PDF |
Available for licensing | |
| Gastroenterology | Alimetry |
Alimetry鈥檚 unique technology non-invasively senses the motility of the stomach to detect the underlying mechanisms of gastric symptoms, informing personalised therapy.
|
Start-Up | |
| Gastroenterology | The Insides Company |
The Insides Company's flagship product, The Insides System, is a medical device that enables chyme to be reinfused into the intestine for enterostomy and enterocutaneous fistula patients.
|
Start-Up | |
| Immunology | Multiplexed tissue imaging |
A novel method for rapid staining and panel iteration for multiplexed tissue imaging.
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Available for licensing | |
| Immunology | Immune monitoring assays using spectral flow cytometry |
Advanced assays for cell characterisation and immunophenotype monitoring.
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Available for licensing | |
| Infectious diseases | Rheumatic fever: A new diagnostic tool |
A new streptococcal serological test to enable efficient and reliable diagnosis of rheumatic fever and post-streptococcal glomerulonephritis.
Download PDF |
Available for licensing | |
| Medical devices | Pressure Vessel Sensor | Implantable pressure monitoring system for detection of physiological fluid changes in blood, brain and bladder. | Available for licensing | |
| Ophthalmology | Toku Eyes |
Ophthalmic imaging device and computational modelling platform to diagnose and monitor eye diseases.
|
Start-Up | |
| Physiotherapy | JUNOFEM |
Pelvic floor pressure sensor and app to help with incontinence and pelvic organ prolapse.
|
Start-Up | |
| Surgery | Apercure Surgical | Radiological and surgical drain devices including a percutaneous catheter fixation device. | Start-Up | |
| Surgery | Avasa | An implantable arterial coupler to help surgeons reconnect microvascular arteries simply and efficiently in tissue transfer and transplant surgery | Start-Up | |
| Surgery | Surgical Canary | A medical device for the early detection of a leak from a gastrointestinal resection via extra-luminal colonic gas collection and sensing. | Available for licensing |